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A Decline in CCL3-5 Chemokine Gene Expression during Primary Simian-Human Immunodeficiency Virus Infection

BACKGROUND: The CC-chemokines CCL3, CCL4 and CCL5 have been found to block the entry of CCR5-tropic HIV into host cells and to suppress the viral replication in vitro, but the in vivo role of endogenous CC-chemokines in HIV-1 infection is still incompletely understood. METHODOLOGY/PRINCIPLE FINDINGS...

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Detalles Bibliográficos
Autores principales: Zhao, Wei, Pahar, Bapi, Borda, Juan T., Alvarez, Xavier, Sestak, Karol
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933601/
https://www.ncbi.nlm.nih.gov/pubmed/17684570
http://dx.doi.org/10.1371/journal.pone.0000726