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Effects of DNA-targeted ionizing radiation produced by 5-[(125)I]iodo-2'-deoxyuridine on global gene expression in primary human cells

BACKGROUND: This study assesses the whole-genome gene expression changes in a panel of primary human cell lines in response to DNA damage mediated by decay of DNA-incorporated radioiodinated thymidine analog 5-[(125)I]iodo-2'-deoxyuridine ((125)I-IUdR). Three normal human cell lines of differen...

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Detalles Bibliográficos
Autores principales: Sokolov, Mykyta V, Neumann, Ronald D, Panyutin, Igor G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934370/
https://www.ncbi.nlm.nih.gov/pubmed/17594496
http://dx.doi.org/10.1186/1471-2164-8-192