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Imputation-Based Analysis of Association Studies: Candidate Regions and Quantitative Traits
We introduce a new framework for the analysis of association studies, designed to allow untyped variants to be more effectively and directly tested for association with a phenotype. The idea is to combine knowledge on patterns of correlation among SNPs (e.g., from the International HapMap project or...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934390/ https://www.ncbi.nlm.nih.gov/pubmed/17676998 http://dx.doi.org/10.1371/journal.pgen.0030114 |