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Imputation-Based Analysis of Association Studies: Candidate Regions and Quantitative Traits

We introduce a new framework for the analysis of association studies, designed to allow untyped variants to be more effectively and directly tested for association with a phenotype. The idea is to combine knowledge on patterns of correlation among SNPs (e.g., from the International HapMap project or...

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Detalles Bibliográficos
Autores principales: Servin, Bertrand, Stephens, Matthew
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934390/
https://www.ncbi.nlm.nih.gov/pubmed/17676998
http://dx.doi.org/10.1371/journal.pgen.0030114