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Combined Effects of Thrombosis Pathway Gene Variants Predict Cardiovascular Events

The genetic background of complex diseases is proposed to consist of several low-penetrance risk loci. Addressing this complexity likely requires both large sample size and simultaneous analysis of different predisposing variants. We investigated the role of four thrombosis genes: coagulation factor...

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Detalles Bibliográficos
Autores principales: Auro, Kirsi, Alanne, Mervi, Kristiansson, Kati, Silander, Kaisa, Kuulasmaa, Kari, Salomaa, Veikko, Peltonen, Leena, Perola, Markus
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934395/
https://www.ncbi.nlm.nih.gov/pubmed/17677000
http://dx.doi.org/10.1371/journal.pgen.0030120