Complex Seizure Disorder Caused by Brunol4 Deficiency in Mice

Idiopathic epilepsy is a common human disorder with a strong genetic component, usually exhibiting complex inheritance. We describe a new mouse mutation in C57BL/6J mice, called frequent-flyer (Ff), in which disruption of the gene encoding RNA-binding protein Bruno-like 4 (Brunol4) leads to limbic a...

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Detalles Bibliográficos
Autores principales: Yang, Yan, Mahaffey, Connie L, Bérubé, Nathalie, Maddatu, Terry P, Cox, Gregory A, Frankel, Wayne N
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934399/
https://www.ncbi.nlm.nih.gov/pubmed/17677002
http://dx.doi.org/10.1371/journal.pgen.0030124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934399/
https://www.ncbi.nlm.nih.gov/pubmed/17677002
http://dx.doi.org/10.1371/journal.pgen.0030124

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