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Variant Surface Glycoprotein gene repertoires in Trypanosoma brucei have diverged to become strain-specific

BACKGROUND: In a mammalian host, the cell surface of African trypanosomes is protected by a monolayer of a single variant surface glycoprotein (VSG). The VSG is central to antigenic variation; one VSG gene is expressed at any one time and there is a low frequency stochastic switch to expression of a...

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Detalles Bibliográficos
Autores principales: Hutchinson, O Clyde, Picozzi, Kim, Jones, Nicola G, Mott, Helen, Sharma, Reuben, Welburn, Susan C, Carrington, Mark
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934917/
https://www.ncbi.nlm.nih.gov/pubmed/17629915
http://dx.doi.org/10.1186/1471-2164-8-234