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Enzymatic incorporation of a third nucleobase pair

DNA polymerases are identified that copy a non-standard nucleotide pair joined by a hydrogen bonding pattern different from the patterns joining the dA:T and dG:dC pairs. 6-Amino-5-nitro-3-(1′-β-d-2′-deoxyribofuranosyl)-2(1H)-pyridone (dZ) implements the non-standard ‘small’ donor–donor–acceptor (py...

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Detalles Bibliográficos
Autores principales: Yang, Zunyi, Sismour, A. Michael, Sheng, Pinpin, Puskar, Nyssa L., Benner, Steven A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934989/
https://www.ncbi.nlm.nih.gov/pubmed/17576683
http://dx.doi.org/10.1093/nar/gkm395