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Structural basis for recognition of cognate tRNA by tyrosyl-tRNA synthetase from three kingdoms

The specific aminoacylation of tRNA by tyrosyl-tRNA synthetases (TyrRSs) relies on the identity determinants in the cognate tRNA(Tyr)s. We have determined the crystal structure of Saccharomyces cerevisiae TyrRS (SceTyrRS) complexed with a Tyr-AMP analog and the native tRNA(Tyr)(GΨA). Structural info...

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Detalles Bibliográficos
Autores principales: Tsunoda, Masaru, Kusakabe, Yoshio, Tanaka, Nobutada, Ohno, Satoshi, Nakamura, Masashi, Senda, Toshiya, Moriguchi, Tomohisa, Asai, Norio, Sekine, Mitsuo, Yokogawa, Takashi, Nishikawa, Kazuya, Nakamura, Kazuo T.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934993/
https://www.ncbi.nlm.nih.gov/pubmed/17576676
http://dx.doi.org/10.1093/nar/gkm417