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Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation
Postreplicative maintenance of genomic methylation patterns was proposed to depend largely on the binding of DNA methyltransferase 1 (Dnmt1) to PCNA, a core component of the replication machinery. We investigated how the slow and discontinuous DNA methylation could be mechanistically linked with fas...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934996/ https://www.ncbi.nlm.nih.gov/pubmed/17576694 http://dx.doi.org/10.1093/nar/gkm432 |