Cargando…
Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation
Postreplicative maintenance of genomic methylation patterns was proposed to depend largely on the binding of DNA methyltransferase 1 (Dnmt1) to PCNA, a core component of the replication machinery. We investigated how the slow and discontinuous DNA methylation could be mechanistically linked with fas...
Autores principales: | Schermelleh, Lothar, Haemmer, Andrea, Spada, Fabio, Rösing, Nicole, Meilinger, Daniela, Rothbauer, Ulrich, Cardoso, M. Cristina, Leonhardt, Heinrich |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934996/ https://www.ncbi.nlm.nih.gov/pubmed/17576694 http://dx.doi.org/10.1093/nar/gkm432 |
Ejemplares similares
-
DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells
por: Spada, Fabio, et al.
Publicado: (2007) -
Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells
por: Meilinger, Daniela, et al.
Publicado: (2009) -
Restricted mobility of Dnmt1 in preimplantation embryos: implications for epigenetic reprogramming
por: Grohmann, Maik, et al.
Publicado: (2005) -
Different Binding Properties and Function of CXXC Zinc Finger Domains in Dnmt1 and Tet1
por: Frauer, Carina, et al.
Publicado: (2011) -
MeCP2 interacts with HP1 and modulates its heterochromatin association during myogenic differentiation
por: Agarwal, Noopur, et al.
Publicado: (2007)