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Different structural states in oligonucleosomes are required for early versus late steps of base excision repair

Chromatin in eukaryotic cells is folded into higher order structures of folded nucleosome filaments, and DNA damage occurs at all levels of this structural hierarchy. However, little is known about the impact of higher order folding on DNA repair enzymes. We examined the catalytic activities of puri...

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Detalles Bibliográficos
Autores principales: Nakanishi, Shima, Prasad, Rajendra, Wilson, Samuel H., Smerdon, Michael
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934998/
https://www.ncbi.nlm.nih.gov/pubmed/17576692
http://dx.doi.org/10.1093/nar/gkm436