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Different structural states in oligonucleosomes are required for early versus late steps of base excision repair
Chromatin in eukaryotic cells is folded into higher order structures of folded nucleosome filaments, and DNA damage occurs at all levels of this structural hierarchy. However, little is known about the impact of higher order folding on DNA repair enzymes. We examined the catalytic activities of puri...
Autores principales: | Nakanishi, Shima, Prasad, Rajendra, Wilson, Samuel H., Smerdon, Michael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934998/ https://www.ncbi.nlm.nih.gov/pubmed/17576692 http://dx.doi.org/10.1093/nar/gkm436 |
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