Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR

Basal transcription of the HIV LTR is highly repressed and requires Tat to recruit the positive transcription elongation factor, P-TEFb, which functions to promote the transition of RNA polymerase II from abortive to productive elongation. P-TEFb is found in two forms in cells, a free, active form a...

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Detalles Bibliográficos
Autores principales: Sedore, Stanley C., Byers, Sarah A., Biglione, Sebastian, Price, Jason P., Maury, Wendy J., Price, David H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1935001/
https://www.ncbi.nlm.nih.gov/pubmed/17576689
http://dx.doi.org/10.1093/nar/gkm443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1935001/
https://www.ncbi.nlm.nih.gov/pubmed/17576689
http://dx.doi.org/10.1093/nar/gkm443

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