SR protein-mediated inhibition of CFTR exon 9 inclusion: molecular characterization of the intronic splicing silencer

The intronic splicing silencer (ISS) of CFTR exon 9 promotes exclusion of this exon from the mature mRNA. This negative influence has important consequences with regards to human pathologic events, as lack of exon 9 correlates well with the occurrence of monosymptomatic and full forms of CF disease....

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Detalles Bibliográficos
Autores principales: Buratti, Emanuele, Stuani, Cristiana, De Prato, Greta, Baralle, Francisco E.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1935002/
https://www.ncbi.nlm.nih.gov/pubmed/17576688
http://dx.doi.org/10.1093/nar/gkm444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1935002/
https://www.ncbi.nlm.nih.gov/pubmed/17576688
http://dx.doi.org/10.1093/nar/gkm444

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