Fine-tuning of intrinsic N-Oct-3 POU domain allostery by regulatory DNA targets

The ‘POU’ (acronym of Pit-1, Oct-1, Unc-86) family of transcription factors share a common DNA-binding domain of approximately 160 residues, comprising so-called ‘POUs’ and ‘POUh’ sub-domains connected by a flexible linker. The importance of POU proteins as developmental regulators and tumor-promoti...

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Detalles Bibliográficos
Autores principales: Alazard, Robert, Mourey, Lionel, Ebel, Christine, Konarev, Peter V., Petoukhov, Maxim V., Svergun, Dmitri I., Erard, Monique
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1935007/
https://www.ncbi.nlm.nih.gov/pubmed/17576670
http://dx.doi.org/10.1093/nar/gkm453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1935007/
https://www.ncbi.nlm.nih.gov/pubmed/17576670
http://dx.doi.org/10.1093/nar/gkm453

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