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Fine-tuning of intrinsic N-Oct-3 POU domain allostery by regulatory DNA targets
The ‘POU’ (acronym of Pit-1, Oct-1, Unc-86) family of transcription factors share a common DNA-binding domain of approximately 160 residues, comprising so-called ‘POUs’ and ‘POUh’ sub-domains connected by a flexible linker. The importance of POU proteins as developmental regulators and tumor-promoti...
Autores principales: | Alazard, Robert, Mourey, Lionel, Ebel, Christine, Konarev, Peter V., Petoukhov, Maxim V., Svergun, Dmitri I., Erard, Monique |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1935007/ https://www.ncbi.nlm.nih.gov/pubmed/17576670 http://dx.doi.org/10.1093/nar/gkm453 |
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