Cargando…
Cytotoxic G-rich oligodeoxynucleotides: putative protein targets and required sequence motif
It has recently been shown that certain oligodeoxynucleotides (ODNs) designed as catalytic DNA molecules (DNAzymes) exhibit potent cytotoxicity independent of RNA-cleavage activity in a number of cell lines. These cytotoxic ODNs all featured a 5′ G-rich sequence and induced cell death by a TLR9-inde...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2007
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1935016/ https://www.ncbi.nlm.nih.gov/pubmed/17586818 http://dx.doi.org/10.1093/nar/gkm465 |