Tau phosphorylation by GSK-3β promotes tangle-like filament morphology

BACKGROUND: Neurofibrillary tangles (NFTs) are intraneuronal aggregates associated with several neurodegenerative diseases including Alzheimer's disease. These abnormal accumulations are primarily comprised of fibrils of the microtubule-associated protein tau. During the progression of NFT form...

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Detalles Bibliográficos
Autores principales: Rankin, Carolyn A, Sun, Qian, Gamblin, Truman C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1936422/
https://www.ncbi.nlm.nih.gov/pubmed/17598919
http://dx.doi.org/10.1186/1750-1326-2-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1936422/
https://www.ncbi.nlm.nih.gov/pubmed/17598919
http://dx.doi.org/10.1186/1750-1326-2-12

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