Cargando…

Tau phosphorylation by GSK-3β promotes tangle-like filament morphology

BACKGROUND: Neurofibrillary tangles (NFTs) are intraneuronal aggregates associated with several neurodegenerative diseases including Alzheimer's disease. These abnormal accumulations are primarily comprised of fibrils of the microtubule-associated protein tau. During the progression of NFT form...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rankin, Carolyn A, Sun, Qian, Gamblin, Truman C
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1936422/ https://www.ncbi.nlm.nih.gov/pubmed/17598919 http://dx.doi.org/10.1186/1750-1326-2-12

Ejemplares similares

GSK-3β phosphorylation of functionally distinct tau isoforms has differential, but mild effects
por: Voss, Kellen, et al.
Publicado: (2009)

Geometrical Constraints on the Tangling of Bacterial Flagellar Filaments
por: Tătulea-Codrean, Maria, et al.
Publicado: (2020)

Tau Phosphorylation by GSK3 in Different Conditions
por: Avila, Jesús, et al.
Publicado: (2012)

It takes more than tau to tangle: using proteomics to determine how phosphorylated tau mediates toxicity in neurodegenerative diseases
por: Pires, Geoffrey, et al.
Publicado: (2021)

The Interplay between GSK3β and Tau Ser262 Phosphorylation during the Progression of Tau Pathology
por: Song, Liqing, et al.
Publicado: (2022)

Tangled tau: Active pathology or footprint of disease?
por: Higham, James P.
Publicado: (2017)

Hsp90 Maintains the Stability and Function of the Tau Phosphorylating Kinase GSK3β
por: Dou, Fei, et al.
Publicado: (2007)

RNA editing of microtubule-associated protein tau circular RNAs promotes their translation and tau tangle formation
por: Welden, Justin Ralph, et al.
Publicado: (2022)

A Tangled Web – Tau and Sporadic Parkinson's Disease
por: Wray, Selina, et al.
Publicado: (2010)

Tau accumulation in the nucleus accumbens in tangle-predominant dementia
por: Kawakami, Ito, et al.
Publicado: (2014)

Aluminum and Tau in Neurofibrillary Tangles in Familial Alzheimer’s Disease
por: Mold, Matthew John, et al.
Publicado: (2021)

Modification of the Drosophila model of in vivo Tau toxicity reveals protective phosphorylation by GSK3β
por: Povellato, Giulia, et al.
Publicado: (2013)

Assessment of Tau Tangles and Amyloid-β Plaques Among Super Agers Using PET Imaging
por: Hoenig, Merle C., et al.
Publicado: (2020)

APOEε4 associates with microglial activation independently of Aβ plaques and tau tangles
por: Ferrari-Souza, João Pedro, et al.
Publicado: (2023)

Salidroside reduces tau hyperphosphorylation via up-regulating GSK-3β phosphorylation in a tau transgenic Drosophila model of Alzheimer’s disease
por: Zhang, Bei, et al.
Publicado: (2016)

Filamentous tangles with nemaline rods in MYH2 myopathy: a novel phenotype
por: Madigan, Nicolas N., et al.
Publicado: (2021)

Disease-Modifying Effects of Non-Invasive Electroceuticals on β-Amyloid Plaques and Tau Tangles for Alzheimer’s Disease
por: Bok, Junsoo, et al.
Publicado: (2022)

Brain delivery of quercetin-loaded exosomes improved cognitive function in AD mice by inhibiting phosphorylated tau-mediated neurofibrillary tangles
por: Qi, Yao, et al.
Publicado: (2020)

CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer’s disease
por: Horie, Kanta, et al.
Publicado: (2023)

Dissociation of tau toxicity and phosphorylation: role of GSK-3β, MARK and Cdk5 in a Drosophila model
por: Chatterjee, Shreyasi, et al.
Publicado: (2009)

Tau mRNA Metabolism in Neurodegenerative Diseases: A Tangle Journey
por: da Costa, Paulo J., et al.
Publicado: (2022)

Fluent molecular mixing of Tau isoforms in Alzheimer’s disease neurofibrillary tangles
por: Dregni, Aurelio J., et al.
Publicado: (2022)

Tangled
por: Soubra, Mahmoud, et al.
Publicado: (2016)

Overexpression of GSK-3β in Adult Tet-OFF GSK-3β Transgenic Mice, and Not During Embryonic or Postnatal Development, Induces Tau Phosphorylation, Neurodegeneration and Learning Deficits
por: Rodríguez-Matellán, Alberto, et al.
Publicado: (2020)

Melatonin Reduces GSK3β-Mediated Tau Phosphorylation, Enhances Nrf2 Nuclear Translocation and Anti-Inflammation
por: Das, Rashmi, et al.
Publicado: (2020)

GSK3α and GSK3β Phosphorylate Arc and Regulate its Degradation
por: Gozdz, Agata, et al.
Publicado: (2017)

Tangles, Toxicity, and Tau Secretion in AD – New Approaches to a Vexing Problem
por: Gendreau, Kerry L., et al.
Publicado: (2013)

Re-examining tau-immunoreactive pathology in the population: granulovacuolar degeneration and neurofibrillary tangles
por: Hunter, Sally, et al.
Publicado: (2015)

Potentiating tangle formation reduces acute toxicity of soluble tau species in the rat
por: d’Orange, Marie, et al.
Publicado: (2018)

Tiny Toes to Tau Tangles: Down's Syndrome and Its Association With Alzheimer's Disease
por: Puttagunta, Sri Madhurima, et al.
Publicado: (2022)

GSK3-β promotes calpain-1–mediated desmin filament depolymerization and myofibril loss in atrophy
por: Aweida, Dina, et al.
Publicado: (2018)

GSK3β and Tau Protein in Alzheimer’s Disease and Epilepsy
por: Toral-Rios, Danira, et al.
Publicado: (2020)

A pharmacological chaperone improves memory by reducing Aβ and tau neuropathology in a mouse model with plaques and tangles
por: Li, Jian-Guo, et al.
Publicado: (2020)

CSF p-tau increase in response to Aβ-type and Danish-type cerebral amyloidosis and in the absence of neurofibrillary tangles
por: Kaeser, Stephan A., et al.
Publicado: (2021)

Extracellular α-Synuclein Leads to Microtubule Destabilization via GSK-3β-Dependent Tau Phosphorylation in PC12 Cells
por: Gąssowska, Magdalena, et al.
Publicado: (2014)

Opposing Roles of GSK3α and GSK3β Phosphorylation in Platelet Function and Thrombosis
por: Moore, Samantha F., et al.
Publicado: (2021)

Highly Selective Tau-SPECT Imaging Probes for Detection of Neurofibrillary Tangles in Alzheimer’s Disease
por: Ono, Masahiro, et al.
Publicado: (2016)

Specific associations between plasma biomarkers and postmortem amyloid plaque and tau tangle loads
por: Salvadó, Gemma, et al.
Publicado: (2023)

Human TAU(P301L) overexpression results in TAU hyperphosphorylation without neurofibrillary tangles in adult zebrafish brain
por: Cosacak, Mehmet I., et al.
Publicado: (2017)

Ser9 phosphorylation of GSK-3β promotes aging in the heart through suppression of autophagy
por: Chen, Yanbin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_51282kbjgkm4vnepi3ennks4it