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Recombinant production of Streptococcus equisimilis streptokinase by Streptomyces lividans
BACKGROUND: Streptokinase (SK) is a potent plasminogen activator with widespread clinical use as a thrombolytic agent. It is naturally secreted by several strains of beta-haemolytic streptococci. The low yields obtained in SK production, lack of developed gene transfer methodology and the pathogenes...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1936427/ https://www.ncbi.nlm.nih.gov/pubmed/17610745 http://dx.doi.org/10.1186/1475-2859-6-20 |