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Secretory granule neuroendocrine protein 1 (SGNE1) genetic variation and glucose intolerance in severe childhood and adult obesity

BACKGROUND: 7B2 is a regulator/activator of the prohormone convertase 2 which is involved in the processing of numerous neuropeptides, including insulin, glucagon and pro-opiomelanocortin. We have previously described a suggestive genetic linkage peak with childhood obesity on chr15q12-q14, where th...

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Detalles Bibliográficos
Autores principales: Bouatia-Naji, Nabila, Vatin, Vincent, Lecoeur, Cécile, Heude, Barbara, Proença, Christine, Veslot, Jacques, Jouret, Béatrice, Tichet, Jean, Charpentier, Guillaume, Marre, Michel, Balkau, Beverley, Froguel, Philippe, Meyre, David
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1936990/
https://www.ncbi.nlm.nih.gov/pubmed/17617923
http://dx.doi.org/10.1186/1471-2350-8-44