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Human T-lymphotropic virus type-1 p30 alters cell cycle G2 regulation of T lymphocytes to enhance cell survival

BACKGROUND: Human T-lymphotropic virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma and is linked to a number of lymphocyte-mediated disorders. HTLV-1 contains both regulatory and accessory genes in four pX open reading frames. pX ORF-II encodes two proteins, p13 and p30, whose roles are st...

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Detalles Bibliográficos
Autores principales: Datta, Antara, Silverman, Lee, Phipps, Andrew J, Hiraragi, Hajime, Ratner, Lee, Lairmore, Michael D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1937004/
https://www.ncbi.nlm.nih.gov/pubmed/17634129
http://dx.doi.org/10.1186/1742-4690-4-49