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Exogenous Interferon-α and Interferon-γ Increase Lethality of Murine Inhalational Anthrax

BACKGROUND: Bacillus anthracis, the etiologic agent of inhalational anthrax, is a facultative intracellular pathogen. Despite appropriate antimicrobial therapy, the mortality from inhalational anthrax approaches 45%, underscoring the need for better adjuvant therapies. The variable latency between e...

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Detalles Bibliográficos
Autores principales: Gold, Jeffrey A., Hoshino, Yoshihiko, Jones, Marcus B., Hoshino, Satomi, Nolan, Anna, Weiden, Michael D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1937023/
https://www.ncbi.nlm.nih.gov/pubmed/17710136
http://dx.doi.org/10.1371/journal.pone.0000736