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Null mutation for Macrophage Migration Inhibitory Factor (MIF) is associated with less aggressive bladder cancer in mice

BACKGROUND: Inflammatory cytokines may promote tumorigenesis. Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine with regulatory properties over tumor suppressor proteins involved in bladder cancer. We studied the development of bladder cancer in wild type (WT) and MIF knocko...

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Detalles Bibliográficos
Autores principales: Taylor, John A, Kuchel, George A, Hegde, Poornima, Voznesensky, Olga S, Claffey, Kevin, Tsimikas, John, Leng, Lin, Bucala, Richard, Pilbeam, Carol
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939709/
https://www.ncbi.nlm.nih.gov/pubmed/17650334
http://dx.doi.org/10.1186/1471-2407-7-135