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TCRζ(dim)lymphocytes define populations of circulating effector cells that migrate to inflamed tissues
The T-cell receptor ζ (TCRζ) chain is a master sensor and regulator of lymphocyte responses. Loss of TCRζ expression has been documented in infectious, inflammatory, and malignant diseases, suggesting that it may serve to limit T-cell reactivity and effector responses at sites of tissue damage. Thes...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939810/ https://www.ncbi.nlm.nih.gov/pubmed/17255353 http://dx.doi.org/10.1182/blood-2006-12-064170 |