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Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy

BACKGROUND: Resistance to modern adjuvant treatment is in part due to the failure of programmed cell death. Therefore the molecules that execute the apoptotic program are potential targets for the development of anti-cancer therapeutics. The sigma-2 receptor has been found to be over-expressed in so...

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Detalles Bibliográficos
Autores principales: Kashiwagi, Hiroyuki, McDunn, Jonathan E, Simon, Peter O, Goedegebuure, Peter S, Xu, Jinbin, Jones, Lynne, Chang, Katherine, Johnston, Fabian, Trinkaus, Kathryn, Hotchkiss, Richard S, Mach, Robert H, Hawkins, William G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939854/
https://www.ncbi.nlm.nih.gov/pubmed/17631687
http://dx.doi.org/10.1186/1476-4598-6-48