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Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy
BACKGROUND: Resistance to modern adjuvant treatment is in part due to the failure of programmed cell death. Therefore the molecules that execute the apoptotic program are potential targets for the development of anti-cancer therapeutics. The sigma-2 receptor has been found to be over-expressed in so...
Autores principales: | Kashiwagi, Hiroyuki, McDunn, Jonathan E, Simon, Peter O, Goedegebuure, Peter S, Xu, Jinbin, Jones, Lynne, Chang, Katherine, Johnston, Fabian, Trinkaus, Kathryn, Hotchkiss, Richard S, Mach, Robert H, Hawkins, William G |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939854/ https://www.ncbi.nlm.nih.gov/pubmed/17631687 http://dx.doi.org/10.1186/1476-4598-6-48 |
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