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Prediction of MHC class II binding affinity using SMM-align, a novel stabilization matrix alignment method

BACKGROUND: Antigen presenting cells (APCs) sample the extra cellular space and present peptides from here to T helper cells, which can be activated if the peptides are of foreign origin. The peptides are presented on the surface of the cells in complex with major histocompatibility class II (MHC II...

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Detalles Bibliográficos
Autores principales: Nielsen, Morten, Lundegaard, Claus, Lund, Ole
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939856/
https://www.ncbi.nlm.nih.gov/pubmed/17608956
http://dx.doi.org/10.1186/1471-2105-8-238