Expression of thymidine phosphorylase in peripheral blood cells of breast cancer patients is not increased by paclitaxel

BACKGROUND: A synergistic cytotoxic effect has been hypothesized for taxanes and capecitabine, a prodrug of 5-fluorouracil. Based on preclinical studies, this synergism has been attributed to an up-regulation of the enzyme thymidine phosphorylase (TP). Beside tumour tissue, TP is highly expressed in...

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Detalles Bibliográficos
Autores principales: Bartsch, Rupert, Steger, Guenther G, Forstner, Birgit, Wenzel, Catharina, Pluschnig, Ursula, Rizovski, Blanka, Altorjai, Gabriela, Zielinski, Christoph C, Mader, Robert M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939983/
https://www.ncbi.nlm.nih.gov/pubmed/17640356
http://dx.doi.org/10.1186/1472-6904-7-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939983/
https://www.ncbi.nlm.nih.gov/pubmed/17640356
http://dx.doi.org/10.1186/1472-6904-7-7

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