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Absence of gemin5 from SMN complexes in nuclear Cajal bodies

BACKGROUND: Spinal muscular atrophy is caused by reduced levels of the survival of motor neurons (SMN) protein. SMN is found in large complexes with Sm proteins and at least eight other proteins, including seven "gemins". These complexes are involved in the assembly of snRNPs in the cytopl...

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Detalles Bibliográficos
Autores principales: Hao, Le thi, Fuller, Heidi R, Lam, Le Thanh, Le, Thanh T, Burghes, Arthur HM, Morris, Glenn E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939999/
https://www.ncbi.nlm.nih.gov/pubmed/17640370
http://dx.doi.org/10.1186/1471-2121-8-28