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Down-regulation of SFRP1 as a putative tumor suppressor gene can contribute to human hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common cancers in the world. SFRP1 (the secreted frizzled-related protein 1), a putative tumor suppressor gene mapped onto chromosome 8p12-p11.1, the frequent loss of heterozygosity (LOH) region in human HCC, encodes a Wingless-type (Wnt)...

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Detalles Bibliográficos
Autores principales: Huang, Jian, Zhang, Yun-Li, Teng, Xiao-Mei, Lin, Yun, Zheng, Da-Li, Yang, Peng-Yuan, Han, Ze-Guang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940018/
https://www.ncbi.nlm.nih.gov/pubmed/17626620
http://dx.doi.org/10.1186/1471-2407-7-126