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Down-regulation of SFRP1 as a putative tumor suppressor gene can contribute to human hepatocellular carcinoma
BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common cancers in the world. SFRP1 (the secreted frizzled-related protein 1), a putative tumor suppressor gene mapped onto chromosome 8p12-p11.1, the frequent loss of heterozygosity (LOH) region in human HCC, encodes a Wingless-type (Wnt)...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940018/ https://www.ncbi.nlm.nih.gov/pubmed/17626620 http://dx.doi.org/10.1186/1471-2407-7-126 |