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Crossregulation and Functional Redundancy between the Splicing Regulator PTB and Its Paralogs nPTB and ROD1

Among the targets of the repressive splicing regulator, polypyrimidine tract binding protein (PTB) is its own pre-mRNA, where PTB-induced exon 11 skipping produces an RNA substrate for nonsense-mediated decay (NMD). To identify additional PTB-regulated alternative splicing events, we used quantitati...

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Detalles Bibliográficos
Autores principales: Spellman, Rachel, Llorian, Miriam, Smith, Christopher W.J.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940037/
https://www.ncbi.nlm.nih.gov/pubmed/17679092
http://dx.doi.org/10.1016/j.molcel.2007.06.016