Cargando…
Crossregulation and Functional Redundancy between the Splicing Regulator PTB and Its Paralogs nPTB and ROD1
Among the targets of the repressive splicing regulator, polypyrimidine tract binding protein (PTB) is its own pre-mRNA, where PTB-induced exon 11 skipping produces an RNA substrate for nonsense-mediated decay (NMD). To identify additional PTB-regulated alternative splicing events, we used quantitati...
Autores principales: | Spellman, Rachel, Llorian, Miriam, Smith, Christopher W.J. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940037/ https://www.ncbi.nlm.nih.gov/pubmed/17679092 http://dx.doi.org/10.1016/j.molcel.2007.06.016 |
Ejemplares similares
-
PTB/nPTB: master regulators of neuronal fate in mammals
por: Hu, Jing, et al.
Publicado: (2018) -
Expression of Human nPTB Is Limited by Extreme Suboptimal Codon Content
por: Robinson, Fiona, et al.
Publicado: (2008) -
The organization of RNA contacts by PTB for regulation of FAS splicing
por: Mickleburgh, Ian, et al.
Publicado: (2014) -
Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB
por: Llorian, Miriam, et al.
Publicado: (2010) -
Solution and crystal structures of a C-terminal fragment of the neuronal isoform of the polypyrimidine tract binding protein (nPTB)
por: Joshi, Amar, et al.
Publicado: (2014)