Modifying Effects of the HFE Polymorphisms on the Association between Lead Burden and Cognitive Decline

BACKGROUND: As iron and lead promote oxidative damage, and hemochromatosis (HFE) gene polymorphisms increase body iron burden, HFE variant alleles may modify the lead burden and cognitive decline relationship. OBJECTIVE: Our goal was to assess the modifying effects of HFE variants on the lead burden...

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Detalles Bibliográficos
Autores principales: Wang, Florence T., Hu, Howard, Schwartz, Joel, Weuve, Jennifer, Spiro, Avron S., Sparrow, David, Nie, Huiling, Silverman, Edwin K., Weiss, Scott T., Wright, Robert O.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940090/
https://www.ncbi.nlm.nih.gov/pubmed/17687449
http://dx.doi.org/10.1289/ehp.9855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940090/
https://www.ncbi.nlm.nih.gov/pubmed/17687449
http://dx.doi.org/10.1289/ehp.9855

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