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Modifying Effects of the HFE Polymorphisms on the Association between Lead Burden and Cognitive Decline

BACKGROUND: As iron and lead promote oxidative damage, and hemochromatosis (HFE) gene polymorphisms increase body iron burden, HFE variant alleles may modify the lead burden and cognitive decline relationship. OBJECTIVE: Our goal was to assess the modifying effects of HFE variants on the lead burden...

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Detalles Bibliográficos
Autores principales:	Wang, Florence T., Hu, Howard, Schwartz, Joel, Weuve, Jennifer, Spiro, Avron S., Sparrow, David, Nie, Huiling, Silverman, Edwin K., Weiss, Scott T., Wright, Robert O.
Formato:	Texto
Lenguaje:	English
Publicado:	National Institute of Environmental Health Sciences 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940090/ https://www.ncbi.nlm.nih.gov/pubmed/17687449 http://dx.doi.org/10.1289/ehp.9855

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