Curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)-1, 6-heptadiene-3,5-dione) Blocks the Chemotaxis of Neutrophils by Inhibiting Signal Transduction through IL-8 Receptors

We investigated the impact of curcumin on neutrophils. Chemotactic activity via human recombinant IL-8 (hrIL-8) was significantly inhibited by curcumin. Curcumin reduced calcium ion flow induced by internalization of the IL-8 receptor. We analyzed flow cytometry to evaluate the status of the IL-8 re...

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Detalles Bibliográficos
Autores principales: Takahashi, Masafumi, Ishiko, Takatoshi, Kamohara, Hidenobu, Hidaka, Hideaki, Ikeda, Osamu, Ogawa, Michio, Baba, Hideo
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940327/
https://www.ncbi.nlm.nih.gov/pubmed/17710245
http://dx.doi.org/10.1155/2007/10767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940327/
https://www.ncbi.nlm.nih.gov/pubmed/17710245
http://dx.doi.org/10.1155/2007/10767

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