Cost-utility analysis of genetic screening in families of patients with germline MUTYH mutations

BACKGROUND: MUTYH associated polyposis (MAP) is an autosomal recessive inherited disorder. Carriers of bi-allelic MUTYH germline mutations have a risk of approximately 60% to develop colorectal carcinoma (CRC). In the general population about 1.5% is a heterozygous MUTYH mutation carrier. Children o...

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Detalles Bibliográficos
Autores principales: Nielsen, Maartje, Hes, Frederik J, Vasen, Hans FA, van den Hout, Wilbert B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1941726/
https://www.ncbi.nlm.nih.gov/pubmed/17605803
http://dx.doi.org/10.1186/1471-2350-8-42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1941726/
https://www.ncbi.nlm.nih.gov/pubmed/17605803
http://dx.doi.org/10.1186/1471-2350-8-42

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