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Cost-utility analysis of genetic screening in families of patients with germline MUTYH mutations
BACKGROUND: MUTYH associated polyposis (MAP) is an autosomal recessive inherited disorder. Carriers of bi-allelic MUTYH germline mutations have a risk of approximately 60% to develop colorectal carcinoma (CRC). In the general population about 1.5% is a heterozygous MUTYH mutation carrier. Children o...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1941726/ https://www.ncbi.nlm.nih.gov/pubmed/17605803 http://dx.doi.org/10.1186/1471-2350-8-42 |