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Gene transfer to pre-hematopoietic and committed hematopoietic precursors in the early mouse Yolk Sac: a comparative study between in situ electroporation and retroviral transduction

BACKGROUND: Hematopoietic development in vertebrate embryos results from the sequential contribution of two pools of precursors independently generated. While intra-embryonic precursors harbour the features of hematopoietic stem cells (HSC), precursors formed earlier in the yolk sac (YS) display lim...

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Detalles Bibliográficos
Autores principales: Giroux, Sébastien JD, Alves-Leiva, Celmar, Lécluse, Yann, Martin, Patrick, Albagli, Olivier, Godin, Isabelle
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1941737/
https://www.ncbi.nlm.nih.gov/pubmed/17605779
http://dx.doi.org/10.1186/1471-213X-7-79