Efficient Construction of an Inverted Minimal H1 Promoter Driven siRNA Expression Cassette: Facilitation of Promoter and siRNA Sequence Exchange

BACKGROUND: RNA interference (RNAi), mediated by small interfering RNA (siRNA), is an effective method used to silence gene expression at the post-transcriptional level. Upon introduction into target cells, siRNAs incorporate into the RNA-induced silencing complex (RISC). The antisense strand of the...

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Detalles Bibliográficos
Autores principales: Nassanian, Hoorig, Sanchez, Ana M., Lo, Alice, Bradley, Kenneth A., Lee, Benhur
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1942083/
https://www.ncbi.nlm.nih.gov/pubmed/17712415
http://dx.doi.org/10.1371/journal.pone.0000767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1942083/
https://www.ncbi.nlm.nih.gov/pubmed/17712415
http://dx.doi.org/10.1371/journal.pone.0000767

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