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Expression and localization of P1 promoter-driven hepatocyte nuclear factor-4α (HNF4α) isoforms in human and rats

BACKGROUND: Hepatocyte nuclear factor-4α (HNF4α; NR2A1) is an orphan member of the nuclear receptor superfamily involved in various processes that could influence endoderm development, glucose and lipid metabolism. A loss-of-function mutation in human HNF4α causes one form of diabetes mellitus calle...

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Detalles Bibliográficos
Autores principales: Jiang, Shuying, Tanaka, Toshiya, Iwanari, Hiroko, Hotta, Hiromitsu, Yamashita, Hisahiko, Kumakura, Junko, Watanabe, Yuichiro, Uchiyama, Yasutoshi, Aburatani, Hiroyuki, Hamakubo, Takao, Kodama, Tatsuhiko, Naito, Makoto
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC194242/
https://www.ncbi.nlm.nih.gov/pubmed/12952540
http://dx.doi.org/10.1186/1478-1336-1-5