Development of Sensory, Motor and Behavioral Deficits in the Murine Model of Sanfilippo Syndrome Type B

BACKGROUND: Mucopolysaccharidosis (MPS) IIIB (Sanfilippo Syndrome type B) is caused by a deficiency in the lysosomal enzyme N-acetyl-glucosaminidase (Naglu). Children with MPS IIIB develop disturbances of sleep, activity levels, coordination, vision, hearing, and mental functioning culminating in ea...

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Detalles Bibliográficos
Autores principales: Heldermon, Coy D., Hennig, Anne K., Ohlemiller, Kevin K., Ogilvie, Judith M., Herzog, Erik D., Breidenbach, Annalisa, Vogler, Carole, Wozniak, David F., Sands, Mark S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1945015/
https://www.ncbi.nlm.nih.gov/pubmed/17712420
http://dx.doi.org/10.1371/journal.pone.0000772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1945015/
https://www.ncbi.nlm.nih.gov/pubmed/17712420
http://dx.doi.org/10.1371/journal.pone.0000772

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