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Myc Dynamically and Preferentially Relocates to a Transcription Factory Occupied by Igh

Transcription in mammalian nuclei is highly compartmentalized in RNA polymerase II-enriched nuclear foci known as transcription factories. Genes in cis and trans can share the same factory, suggesting that genes migrate to preassembled transcription sites. We used fluorescent in situ hybridization t...

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Detalles Bibliográficos
Autores principales: Osborne, Cameron S, Chakalova, Lyubomira, Mitchell, Jennifer A, Horton, Alice, Wood, Andrew L, Bolland, Daniel J, Corcoran, Anne E, Fraser, Peter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1945077/
https://www.ncbi.nlm.nih.gov/pubmed/17622196
http://dx.doi.org/10.1371/journal.pbio.0050192