A Dimer of the Toll-Like Receptor 4 Cytoplasmic Domain Provides a Specific Scaffold for the Recruitment of Signalling Adaptor Proteins

The Toll-like receptor 4 (TLR4) is a class I transmembrane receptor expressed on the surface of immune system cells. TLR4 is activated by exposure to lipopolysaccharides derived from the outer membrane of Gram negative bacteria and forms part of the innate immune response in mammals. Like other clas...

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Detalles Bibliográficos
Autores principales: Núñez Miguel, Ricardo, Wong, Joyce, Westoll, Julian F., Brooks, Heather J., O'Neill, Luke A.J., Gay, Nicholas J., Bryant, Clare E., Monie, Tom P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1945083/
https://www.ncbi.nlm.nih.gov/pubmed/17726518
http://dx.doi.org/10.1371/journal.pone.0000788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1945083/
https://www.ncbi.nlm.nih.gov/pubmed/17726518
http://dx.doi.org/10.1371/journal.pone.0000788

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