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The antiestrogen ICI 182,780 induces early effects on the adult male mouse reproductive tract and long-term decreased fertility without testicular atrophy

BACKGROUND: Estrogen receptors (ER) have important physiological roles in both the female and male reproductive systems. Previous studies using the estrogen receptor-α knockout mouse (αERKO) or antiestrogen treatment in adult rodents have shown that ERα is essential for normal function of the male r...

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Detalles Bibliográficos
Autores principales: Cho, Hyun Wook, Nie, Rong, Carnes, Kay, Zhou, Qing, Sharief, Noaman AQ, Hess, Rex A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC194658/
https://www.ncbi.nlm.nih.gov/pubmed/12959643
http://dx.doi.org/10.1186/1477-7827-1-57