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Pharmacogenetic heterogeneity of transgene expression in muscle and tumours

BACKGROUND: Recombinant adenoviruses are employed to deliver a therapeutic transgene in the liver, muscle or tumour tissue. However, to rationalise this delivery approach, the factors of variation between individuals need to be identified. It is assumed that differences between inbred strains of lab...

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Detalles Bibliográficos
Autores principales: Lefesvre, Pierre, Attema, Joline, van Bekkum, Dirk
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC194725/
https://www.ncbi.nlm.nih.gov/pubmed/12943556
http://dx.doi.org/10.1186/1471-2210-3-11