Expression of hereditary hemochromatosis C282Y HFE protein in HEK293 cells activates specific endoplasmic reticulum stress responses

BACKGROUND: Hereditary Hemochromatosis (HH) is a genetic disease associated with iron overload, in which individuals homozygous for the mutant C282Y HFE associated allele are at risk for the development of a range of disorders particularly liver disease. Conformational diseases are a class of disord...

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Detalles Bibliográficos
Autores principales: Lawless, Matthew W, Mankan, Arun K, White, Mary, O'Dwyer, Michael J, Norris, Suzanne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1947972/
https://www.ncbi.nlm.nih.gov/pubmed/17650303
http://dx.doi.org/10.1186/1471-2121-8-30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1947972/
https://www.ncbi.nlm.nih.gov/pubmed/17650303
http://dx.doi.org/10.1186/1471-2121-8-30

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