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Running on a treadmill: dynamic inhibition of APC/C by the spindle checkpoint
During mitosis, the genome duplicated during S-phase is synchronously and accurately segregated to the two daughter cells. The spindle checkpoint prevents premature sister-chromatid separation and mitotic exit. The anaphase-promoting complex/cyclosome (APC/C) is a key target of the spindle checkpoin...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1947974/ https://www.ncbi.nlm.nih.gov/pubmed/17650307 http://dx.doi.org/10.1186/1747-1028-2-23 |