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Fanconi anemia genes are highly expressed in primitive CD34(+ )hematopoietic cells

BACKGROUND: Fanconi anemia (FA) is a complex recessive genetic disease characterized by progressive bone marrow failure (BM) and a predisposition to cancer. We have previously shown using the Fancc mouse model that the progressive BM failure results from a hematopoietic stem cell defect suggesting t...

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Detalles Bibliográficos
Autores principales: Aubé, Michel, Lafrance, Matthieu, Brodeur, Isabelle, Delisle, Marie-Chantal, Carreau, Madeleine
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC194856/
https://www.ncbi.nlm.nih.gov/pubmed/12809565
http://dx.doi.org/10.1186/1471-2326-3-1