The acute neurotoxicity of mefloquine may be mediated through a disruption of calcium homeostasis and ER function in vitro

BACKGROUND: There is no established biochemical basis for the neurotoxicity of mefloquine. We investigated the possibility that the acute in vitro neurotoxicity of mefloquine might be mediated through a disruptive effect of the drug on endoplasmic reticulum (ER) calcium homeostasis. METHODS: Laser s...

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Detalles Bibliográficos
Autores principales: Dow, Geoffrey S, Hudson, Thomas H, Vahey, Maryanne, Koenig, Michael L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC194860/
https://www.ncbi.nlm.nih.gov/pubmed/12848898
http://dx.doi.org/10.1186/1475-2875-2-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC194860/
https://www.ncbi.nlm.nih.gov/pubmed/12848898
http://dx.doi.org/10.1186/1475-2875-2-14

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